Serving CA, CT, FL, HI, NJ, NY, NC, TX

Why I Don’t Recommend The DUTCH Test

Why I Don't Order the DUTCH Test for My Patients

Written by: Dr. Sarah Musleh, Endocrinologist at Anzara Health

Published: 01-19-2024

Is The DUTCH test legitimate? This question is valid, especially considering the costs of this test and the big claims around this diagnostic tool.

As an endocrinologist committed to evidence-based medicine, I’m cautious about incorporating the DUTCH test into my practice.

In this article, I will explore the reasons that make me skeptical, from the test’s lack of validation to its inherent shortcomings when informing clinical decisions.

Understanding the DUTCH Test

The DUTCH test’s popularity stems from its two main premises: 1) the manufacturer claims it can identify conditions such as hormonal imbalances, and 2) test samples can be conveniently collected at home via dry urine. 

While there are studies validating that dry urine tests can measure basic hormone levels through metabolites as accurately as blood serum tests, they are costly alternatives (the least expensive DUCTH test costs $299), usually not covered by insurance. 

Claims like “it can identify symptoms of hormonal imbalances” are unsubstantiated and require more than measuring hormones and metabolites. 

The DUTCH Test's Lack of Validation

While intriguing in theory, the DUTCH test requires more extensive scientific validation for widespread clinical acceptance.

Some of the studies that validate the effectiveness of dried urine hormone tests have been conducted by the test’s manufacturing group

Published, peer-reviewed studies supporting its reliability and reproducibility are notably scarce.

Its ability to take a snapshot of many different hormones at a time is promising, but that doesn’t guarantee that a doctor can pinpoint any specific condition or disease.

The correlation between DUTCH test results and clinical symptoms that lead to a successful diagnostic must be more consistent for it to have the clinical utility that it claims.

image of an endocrinologist prescribing hormone tests to a patient

Shortcomings of the DUTCH Test

As mentioned above, a snapshot of several hormones at any given time doesn’t equate to an instant diagnosis. Below, I’ve outlined several shortcomings of the DUTCH Test.

1. Static Snapshot vs. Dynamic Hormonal Changes

Hormones exhibit dynamic fluctuations throughout the day, following circadian rhythms. The DUTCH test captures a static snapshot, potentially missing crucial diurnal variations essential for understanding hormonal balance.

2. External Factors Impacting Metabolite Levels

The interpretation of metabolites in the DUTCH test is challenging due to the influence of external factors.

Diet, medications, and other lifestyle variables can significantly impact metabolite levels, introducing confounding variables into the analysis.

3. Reliance on Patient-Reported Symptoms

The DUTCH test often relies on patients self-reporting symptoms, introducing subjectivity into the assessment.

Patients may need to report symptoms, leading to potential misinterpretation of results accurately.

4. Incomplete Coverage of Hormonal Imbalances:

While the DUTCH test covers a range of hormones, it may only provide a comprehensive assessment of some hormonal imbalances.

Specific endocrine disorders may require additional, validated testing methods for accurate diagnosis. Moreover, hormone levels don’t necessarily correlate to actual conditions. 

Cortisol level measurements, for instance, didn’t correlate to 50%-80% of patient’s chronic fatigue symptoms within a comprehensive meta-analysis.

My Final Thoughts on the DUTCH Test

While the DUTCH test seems enticing in its potential to offer insights into hormonal health, its lack of validation and inherent shortcomings raise significant concerns.

As an endocrinologist committed to evidence-based medicine, I rely solely on robust clinical evidence to make informed decisions about patient care.

I can only endorse its use as a standalone diagnostic tool once the DUTCH test undergoes extensive validation and addresses its limitations.

About Anzara Health

Anzara Health is a multi-state concierge endocrinology practice providing highly personalized care through telemedicine. 

Driven by a team of healthcare professionals, we are committed to delivering actionable and evidence-based solutions to improve your health and holistic well-being. 

Taking advantage of the latest scientific evidence, we create individualized plans to ensure an effective use of testing and treatments.

Start your journey toward better health today—don’t hesitate to schedule an appointment with us.


Get our latest articles
Skip to content